(ii) presence of a distinctive deficit seen in visual contrast sensitivity (VCS)

(i) increased relative risk for specific HLA haplotypes Proteomic biomarkers compared to controls include These biomarkers include symptom clusters for CIRS acquired following environmental exposures to biotoxins and inflammagens in water-damaged buildings (WDB), finding at least 8 of 13 clusters present. …The difference is that CIRS literature has data on many recognized biomarkers and a published treatment protocol, but PICS does not. – Elevated levels of myelin basic protein antibodies” – Presence of MARCoNS in deep nasal spaces – Reduction of MMP9, if elevated, with treatment – Reduction of leptin, if elevated, with treatment – Response to CSM, with abatement of symptoms and resolution of VCS deficit to control levels – presence of multiple symptoms in at least 4 of 8 system categories – potential for exposure to buildings with a documented toxigenic fungi, evident fungal growth or a history of water intrusion with musty smells We propose that a definition of a case of SBS include each of the following elements Shoemaker’s original Sick Building Syndrome (SBS) criteria from 2003 (note, this was before the discovery of C4a and TGF-b1 being elevated, and VIP being lowered, in CIRS):ġ. Whether this means the patients has CIRS, mycotoxicosis or mycotoxins coming from a normal diet is matter of some debate.įrom Dr. Other doctors will diagnose on other testing such as a positive urinary mycotoxin test. Sandeep Gupta said “Once you have around 3 abnormal markers, that should be sufficient.” Speaking on the Low Tox Life podcast ( #55, 50m02s) Dr. Shoemaker said at least 3 of 6 of biomarkers (known at that time) if symptom and environmental criteria were met. No one test, or even a panel, can diagnose CIRS with 100% accuracy. What test will diagnose me with CIRS/Mould Illness?ĭiagnosis should first and foremost be made by a CIRS/mould-aware health practitioner looking at a patient’s symptoms and diagnoses, health history, and environmental history in conjunction with biomarker testing. Lyme, tick-borne disease and stealth infections.Volumetric MRI Brain Imaging (NeuroQuant) (Partly rebate-able).Nasal swab for MARCoNS and Fungi (Out-of-pocket).Organic Acids Testing (OAT) (Out-of-pocket).Serum mycotoxin antibodies (Out-of-pocket).Urinary mycotoxin tests (Out-of-pocket).Blood tests – NutriPATH (Out-of-pocket).Blood tests (Not currently available from a NATA accredited Australian lab).Visual contrast sensitivity (VCS) (Free or low cost).What test will diagnose me with CIRS/Mould Illness?.Update: This page also has an accompanying Google sheet

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